active transport Archive

  • From Biological Spectra (multiple protein binding data) to pharmacological profiling!

    From Biological Spectra (multiple protein binding data) to pharmacological profiling!

    An ideal drug cures a decease and does not kill a patient (or even lab animals in the course of preclinical testing). Usual drug discovery paradigm is based on studying a compound’s properties against a specific, normally decease-related (protein) target. The ability of a compound...

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  • From binding data to pharmacokinetics: a novel approach to active drug absorbtion prediction

    From binding data to pharmacokinetics: a novel approach to active drug absorbtion prediction

    Oral administered drugs are mainly absorbed in the small intestine. Here, depending on drug composition and size, absorption can happen through a variety of processes . Through the epithelial cells and the lamina pro- pria the drug passes from the lumen into the blood stream...

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