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	<title>Quantum Discovery Labs &#187; druglikeness</title>
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		<title>Does size matter?</title>
		<link>http://q-pharm.com/2010/04/does-size-matter/</link>
		<comments>http://q-pharm.com/2010/04/does-size-matter/#comments</comments>
		<pubDate>Fri, 23 Apr 2010 09:37:58 +0000</pubDate>
		<dc:creator>Peter Fedichev, Quantum CTO</dc:creator>
				<category><![CDATA[druglikeness]]></category>
		<category><![CDATA[openbabel]]></category>
		<category><![CDATA[toxicity]]></category>

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		<description><![CDATA[The goal of drug discovery is to find potent and selective inhibitors for particular targets. A good ligand thus should be small (for better bio-availability) and potent. The larger is...
No related posts.]]></description>
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		<slash:comments>1</slash:comments>
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		<title>Do we need those nM-inhibitors?</title>
		<link>http://q-pharm.com/2009/11/do-we-need-those-nm-inhibitors/</link>
		<comments>http://q-pharm.com/2009/11/do-we-need-those-nm-inhibitors/#comments</comments>
		<pubDate>Wed, 11 Nov 2009 13:46:28 +0000</pubDate>
		<dc:creator>Peter Fedichev, Quantum CTO</dc:creator>
				<category><![CDATA[druglikeness]]></category>
		<category><![CDATA[LD50]]></category>
		<category><![CDATA[MRDD]]></category>
		<category><![CDATA[toxicity]]></category>

		<guid isPermaLink="false">http://q-pharm.com/?p=122</guid>
		<description><![CDATA[It&#8217;s &#8220;well known&#8221; that we all need to find the stronger inhibitors against any specific therapeutic target as possible. The motivation is that the strongest inhibitors are most probably less...
Related posts:<ol>
<li><a href='http://q-pharm.com/2010/04/does-size-matter/' rel='bookmark' title='Does size matter?'>Does size matter?</a></li>
<li><a href='http://q-pharm.com/2008/01/drug-likeness-what-do-bioavailability-and-toxicity-properties-tell-us-about-druglikeness/' rel='bookmark' title='Drug likeness: what do bioavailability and toxicity properties tell us about druglikeness?'>Drug likeness: what do bioavailability and toxicity properties tell us about druglikeness?</a></li>
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		<slash:comments>1</slash:comments>
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		<title>How drug-like are vendor libraries?</title>
		<link>http://q-pharm.com/2009/10/how-drug-like-are-vendor-libraries/</link>
		<comments>http://q-pharm.com/2009/10/how-drug-like-are-vendor-libraries/#comments</comments>
		<pubDate>Mon, 26 Oct 2009 17:24:24 +0000</pubDate>
		<dc:creator>Peter Fedichev, Quantum CTO</dc:creator>
				<category><![CDATA[compound libraries]]></category>
		<category><![CDATA[druglikeness]]></category>
		<category><![CDATA[mechanism of action exploration]]></category>
		<category><![CDATA[toxicity]]></category>

		<guid isPermaLink="false">http://q-pharm.com/?p=63</guid>
		<description><![CDATA[We use a few chemical compounds vendors in our drug discovery programs (let us call them &#8220;Provider I&#8221;, &#8220;Provider II&#8221;, and &#8220;Provider III&#8221;). Nowadays chemicals providers normally claim about 1M...
Related posts:<ol>
<li><a href='http://q-pharm.com/quantum-discovery-services/drug-leads-design/' rel='bookmark' title='Drug Leads Design'>Drug Leads Design</a></li>
</ol>]]></description>
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		<slash:comments>0</slash:comments>
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		<title>Drug likeness: what do bioavailability and toxicity properties tell us about druglikeness?</title>
		<link>http://q-pharm.com/2008/01/drug-likeness-what-do-bioavailability-and-toxicity-properties-tell-us-about-druglikeness/</link>
		<comments>http://q-pharm.com/2008/01/drug-likeness-what-do-bioavailability-and-toxicity-properties-tell-us-about-druglikeness/#comments</comments>
		<pubDate>Wed, 09 Jan 2008 10:37:00 +0000</pubDate>
		<dc:creator>fedichev</dc:creator>
				<category><![CDATA[bioavailability]]></category>
		<category><![CDATA[druglikeness]]></category>
		<category><![CDATA[MRDD]]></category>
		<category><![CDATA[toxicity]]></category>

		<guid isPermaLink="false">http://q-pharm.com/?p=21</guid>
		<description><![CDATA[Druglikeness is a qualitative concept used in drug design for an estimate on how &#8220;druglike&#8221; a prospective compound is. Usually it is estimated from the molecular structure, often even before...
Related posts:<ol>
<li><a href='http://q-pharm.com/quantum-discovery-services/toxicity-prediction/' rel='bookmark' title='Toxicity Prediction'>Toxicity Prediction</a></li>
<li><a href='http://q-pharm.com/2010/04/does-size-matter/' rel='bookmark' title='Does size matter?'>Does size matter?</a></li>
<li><a href='http://q-pharm.com/2009/10/how-drug-like-are-vendor-libraries/' rel='bookmark' title='How drug-like are vendor libraries?'>How drug-like are vendor libraries?</a></li>
<li><a href='http://q-pharm.com/2009/11/do-we-need-those-nm-inhibitors/' rel='bookmark' title='Do we need those nM-inhibitors?'>Do we need those nM-inhibitors?</a></li>
<li><a href='http://q-pharm.com/2008/01/ld50-vs-mrdd-whats-death-for-a-mice-is-good-enough-for-a-man/' rel='bookmark' title='LD50 vs. MRDD: what&#8217;s death for a mice is good enough for a man'>LD50 vs. MRDD: what&#8217;s death for a mice is good enough for a man</a></li>
</ol>]]></description>
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