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	<title>Quantum Discovery Labs &#187; MRDD</title>
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		<title>Do we need those nM-inhibitors?</title>
		<link>http://q-pharm.com/2009/11/do-we-need-those-nm-inhibitors/</link>
		<comments>http://q-pharm.com/2009/11/do-we-need-those-nm-inhibitors/#comments</comments>
		<pubDate>Wed, 11 Nov 2009 13:46:28 +0000</pubDate>
		<dc:creator>Peter Fedichev, Quantum CTO</dc:creator>
				<category><![CDATA[druglikeness]]></category>
		<category><![CDATA[LD50]]></category>
		<category><![CDATA[MRDD]]></category>
		<category><![CDATA[toxicity]]></category>

		<guid isPermaLink="false">http://q-pharm.com/?p=122</guid>
		<description><![CDATA[It&#8217;s &#8220;well known&#8221; that we all need to find the stronger inhibitors against any specific therapeutic target as possible. The motivation is that the strongest inhibitors are most probably less...
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		<title>LD50 vs. MRDD: what&#8217;s death for a mice is good enough for a man</title>
		<link>http://q-pharm.com/2008/01/ld50-vs-mrdd-whats-death-for-a-mice-is-good-enough-for-a-man/</link>
		<comments>http://q-pharm.com/2008/01/ld50-vs-mrdd-whats-death-for-a-mice-is-good-enough-for-a-man/#comments</comments>
		<pubDate>Thu, 24 Jan 2008 20:00:00 +0000</pubDate>
		<dc:creator>fedichev</dc:creator>
				<category><![CDATA[LD50]]></category>
		<category><![CDATA[MRDD]]></category>
		<category><![CDATA[toxicity]]></category>

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		<description><![CDATA[Prediction of toxic properties of small drug like molecules is a big challenge both from theoretical and practical points of view. Quantitatively people use different measures of toxicity such as...
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</ol>]]></description>
		<wfw:commentRss>http://q-pharm.com/2008/01/ld50-vs-mrdd-whats-death-for-a-mice-is-good-enough-for-a-man/feed/</wfw:commentRss>
		<slash:comments>0</slash:comments>
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		<title>Drug likeness: what do bioavailability and toxicity properties tell us about druglikeness?</title>
		<link>http://q-pharm.com/2008/01/drug-likeness-what-do-bioavailability-and-toxicity-properties-tell-us-about-druglikeness/</link>
		<comments>http://q-pharm.com/2008/01/drug-likeness-what-do-bioavailability-and-toxicity-properties-tell-us-about-druglikeness/#comments</comments>
		<pubDate>Wed, 09 Jan 2008 10:37:00 +0000</pubDate>
		<dc:creator>fedichev</dc:creator>
				<category><![CDATA[bioavailability]]></category>
		<category><![CDATA[druglikeness]]></category>
		<category><![CDATA[MRDD]]></category>
		<category><![CDATA[toxicity]]></category>

		<guid isPermaLink="false">http://q-pharm.com/?p=21</guid>
		<description><![CDATA[Druglikeness is a qualitative concept used in drug design for an estimate on how &#8220;druglike&#8221; a prospective compound is. Usually it is estimated from the molecular structure, often even before...
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</ol>]]></description>
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