Quantum Pharmaceuticals » selectivity http://q-pharm.com The drug discovery company Thu, 05 Aug 2010 15:05:38 +0000 en hourly 1 http://wordpress.org/?v=3.0.1 Application of a novel in silico high throughput screen to identify selective inhibitors for protein–protein interactions http://q-pharm.com/2010/08/application-of-a-novel-in-silico-high-throughput-screen-to-identify-selective-inhibitors-for-protein%e2%80%93protein-interactions/ http://q-pharm.com/2010/08/application-of-a-novel-in-silico-high-throughput-screen-to-identify-selective-inhibitors-for-protein%e2%80%93protein-interactions/#comments Thu, 05 Aug 2010 15:05:38 +0000 Peter Fedichev, Quantum CTO http://q-pharm.com/?p=334
  • Quantum Pharmaceuticals announce collaboration with University of Colorado at Boulder
  • Drug Discovery: identifying potential therapeutics that inhibit opioids-induced glial cell activation
  • QUANTUM and albumin binding calculations: the role of protein flexibility
  • Protein Flexibility and False Positives detection.
  • New inhibitors of RecA (bacterial SOS response system) identified.
    • Related posts brought to you by Yet Another Related Posts Plugin.]]>     http://q-pharm.com/2010/08/application-of-a-novel-in-silico-high-throughput-screen-to-identify-selective-inhibitors-for-protein%e2%80%93protein-interactions/feed/ 0     Drug resistance: evolution in action http://q-pharm.com/2010/01/drug-resistance-evolution-in-action/ http://q-pharm.com/2010/01/drug-resistance-evolution-in-action/#comments Wed, 06 Jan 2010 08:40:08 +0000 Peter Fedichev, Quantum CTO http://q-pharm.com/?p=176
  • QUANTUM and albumin binding calculations: the role of protein flexibility
  • Does hERG binding correlate with LogP?
  • What’s an ultimate value of reversible drug binding constant?
  • New inhibitors of RecA (bacterial SOS response system) identified.
  • Quantum Science Overview, v 0.1 has been released
    • Related posts brought to you by Yet Another Related Posts Plugin.]]>     http://q-pharm.com/2010/01/drug-resistance-evolution-in-action/feed/ 1     Docking selectivity: Additive vs. non-additive force field http://q-pharm.com/2007/04/docking-selectivity-additive-vs-non-additive-force-field/ http://q-pharm.com/2007/04/docking-selectivity-additive-vs-non-additive-force-field/#comments Thu, 19 Apr 2007 14:03:00 +0000 fedichev http://q-pharm.com/?p=10
  • QUANTUM free energy vs. statistical scoring functions
  • Protein Flexibility and False Positives detection.
  • Docking validation study: PDK1-kinase (oncology)
  • What makes a correct binding energy calculation?
  • Docking validation study: classic example, thrombine
    • Related posts brought to you by Yet Another Related Posts Plugin.]]>     http://q-pharm.com/2007/04/docking-selectivity-additive-vs-non-additive-force-field/feed/ 0